Leading science, pioneering therapies
Preserving transcriptional potency while driving embryonic stem cell differentiation

Preserving transcriptional potency while driving embryonic stem cell differentiation

Event Date
26 April 2018 - 12:00 to 13:00
Add to Calendar
Location
CRM Seminar Room
Speaker Name
Prof. Josh Brickman
Speaker Organisation
Novo Nordisk Foundation Centre, University of Copenhagen
Host

 

Using embryonic stem cells as a model, Prof. Brickman will discuss his model for how transcriptional competence to re-activate pluripotency genes is maintained during differentiation.  These mechanisms suggest simple paradigms for regulative early mammalian development that could allow for transcriptional stochasticity while promoting reversible, but precisely controlled cell fate choice.