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RNA function in germ and stem cell biology group publications

2018

Vasiliauskaite L, Berrens RV, Ivanova I, Carrieri C, Reik W, Enright AJ, O'Carroll D.  2018.  Defective germline reprogramming rewires the spermatogonial transcriptome.Nat Struct Mol Biol. 25(5):394-404.
Le Pen J, Jiang H, Di Domenico T, Kneuss E, Kosałka J, Leung C, Morgan M, Much C, Rudolph KLM, Enright AJ et al..  2018.  Terminal uridylyltransferases target RNA viruses as part of the innate immune system.Nat Struct Mol Biol. 25(9):778-786.

2017

Wasserman GA, Szymaniak AD, Hinds AC, Yamamoto K, Kamata H, Smith NMs, Hilliard KL, Carrieri C, Labadorf AT, Quinton LJ et al..  2017.  Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.J Clin Invest.
Ivanova I, Much C, Di Giacomo M, Azzi C, Morgan M, Moreira PN, Monahan J, Carrieri C, Enright AJ, O'Carroll D.  2017.  The RNA m(6)A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence.Mol Cell.
Morgan M, Much C, DiGiacomo M, Azzi C, Ivanova I, Vitsios DM, Pistolic J, Collier P, Moreira PN, Benes V et al..  2017.  mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome.Nature. 548(7667):347-351.
Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez N-GP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ et al..  2017.  The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.PLoS One. 12(6):e0179797.
Carrieri C, Comazzetto S, Grover A, Morgan M, Buness A, Nerlov C, O'Carroll D.  2017.  A transit-amplifying population underpins the efficient regenerative capacity of the testis.J Exp Med.
Davis MP, Carrieri C, Saini HK, van Dongen S, Leonardi T, Bussotti G, Monahan JM, Auchynnikava T, Bitetti A, Rappsilber J et al..  2017.  Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution.EMBO Rep.
Vasiliauskaite L, Vitsios D, Berrens RV, Carrieri C, Reik W, Enright AJ, O'Carroll D.  2017.  A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming.Nat Struct Mol Biol.
Guitart A, Panagopoulou TI, Villacreces A, Vukovic M, Sepulveda C, Allen L, Carter RN, van de Lagemaat LN, Morgan M, Giles P et al..  2017.  Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.J Exp Med. 214(3):719-735.

2016

Much C, Auchynnikava T, Pavlinic D, Buness A, Rappsilber J, Benes V, Allshire R, O'Carroll D.  2016.  Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein.PLoS Genet. 12(6):e1006095.

2015

Vukovic M, Guitart A, Sepulveda C, Villacreces A, O'Duibhir E, Panagopoulou TI, Ivens A, Menendez-Gonzalez J, Iglesias JManuel, Allen L et al..  2015.  Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.J Exp Med. 212(13):2223-34.

2014

Tattikota SG, Rathjen T, McAnulty SJ, Wessels H-H, Akerman I, van de Bunt M, Hausser J, Esguerra JLS, Musahl A, Pandey AK et al..  2014.  Argonaute2 mediates compensatory expansion of the pancreatic β cell.Cell Metab. 19(1):122-34.
Comazzetto S, Di Giacomo M, Rasmussen KDindler, Much C, Azzi C, Perlas E, Morgan M, O'Carroll D.  2014.  Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci.PLoS Genet. 10(10):e1004597.
Di Giacomo M, Comazzetto S, Sampath SC, Sampath SC, O'Carroll D.  2014.  G9a co-suppresses LINE1 elements in spermatogonia.Epigenetics Chromatin. 7:24.
Grover A, Mancini E, Moore S, Mead AJ, Atkinson D, Rasmussen KD, O'Carroll D, Jacobsen SEirik W, Nerlov C.  2014.  Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate.J Exp Med. 211(2):181-8.

2013

Tan CLek, Plotkin JL, Venø MT, von Schimmelmann M, Feinberg P, Mann S, Handler A, Kjems J, D Surmeier J, O'Carroll D et al..  2013.  MicroRNA-128 governs neuronal excitability and motor behavior in mice.Science. 342(6163):1254-8.
Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M, Vasiliauskaite L, Benes V, Enright AJ, O'Carroll D.  2013.  Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.Mol Cell. 50(4):601-8.
O'Carroll D, Schaefer A.  2013.  General principals of miRNA biogenesis and regulation in the brain.Neuropsychopharmacology. 38(1):39-54.

2012

Buza-Vidas N, Cismasiu VB, Moore S, Mead AJ, Woll PS, Lutteropp M, Melchiori L, Luc S, Bouriez-Jones T, Atkinson D et al..  2012.  Dicer is selectively important for the earliest stages of erythroid development.Blood. 120(12):2412-6.

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