Leading science, pioneering therapies

Neural stem cells and brain cancer group publications

2017

Bressan RBardini, Dewari PSingh, Kalantzaki M, Gangoso E, Matjusaitis M, Garcia-Diaz C, Blin C, Grant V, Bulstrode H, Gogolok S et al..  2017.  Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.Development. 144(4):635-648.

2016

Pollard SM.  2016.  Quantitative stem cell biology: the threat and the glory.Development. 143(22):4097-4100.
Okawa S, Gagrica S, Blin C, Ender C, Pollard SM, Krijgsveld J.  2016.  Proteome and Secretome Characterization of Glioblastoma-Derived Neural Stem Cells.Stem Cells.
Carén H, Beck S, Pollard SM.  2016.  Differentiation therapy for glioblastoma – too many obstacles?Molecular & Cellular Oncology. 3(2):e1124174.
Martella A, Pollard SM, Dai J, Cai Y.  2016.  Mammalian Synthetic Biology: Time for Big MACs.ACS Synth Biol.
Garros-Regulez L, Aldaz P, Arrizabalaga O, Moncho-Amor V, Carrasco-Garcia E, Manterola L, Moreno-Cugnon L, Barrena C, Villanua J, Ruiz I et al..  2016.  mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.Expert Opin Ther Targets. 20(4):393-405.
Pollard SM, M Marqués-Torrejón Á.  2016.  Give it a REST!Elife. 5

2015

Carén H, Stricker SH, Bulstrode H, Gagrica S, Johnstone E, Bartlett TE, Feber A, Wilson G, Teschendorff AE, Bertone P et al..  2015.  Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest.Stem Cell Reports.
Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H et al..  2015.  Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.Cell Rep.

2014

2013

Stricker SH, Feber A, Engström PG, Carén H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P et al..  2013.  Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner.Genes Dev. 27(6):654-69.
Carén H, Pollard SM, Beck S.  2013.  The good, the bad and the ugly: epigenetic mechanisms in glioblastoma.Mol Aspects Med. 34(4):849-62.
Pollard SM.  2013.  In vitro expansion of fetal neural progenitors as adherent cell lines.Methods Mol Biol. 1059:13-24.
Sofueva S, Yaffe E, Chan W-C, Georgopoulou D, Rudan MVietri, Mira-Bontenbal H, Pollard SM, Schroth GP, Tanay A, Hadjur S.  2013.  Cohesin-mediated interactions organize chromosomal domain architecture.EMBO J. 32(24):3119-29.
Ding Y, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK et al..  2013.  Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells.Cancer Discov. 3(2):198-211.
Hubert CG, Bradley RK, Ding Y, Toledo CM, Herman J, Skutt-Kakaria K, Girard EJ, Davison J, Berndt J, Corrin P et al..  2013.  Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.Genes Dev. 27(9):1032-45.
Danovi D, Folarin A, Gogolok S, Ender C, Elbatsh AMO, Engström PG, Stricker SH, Gagrica S, Georgian A, Yu D et al..  2013.  A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.PLoS One. 8(10):e77053.

2012

Danovi D, Folarin AA, Baranowski B, Pollard SM.  2012.  High content screening of defined chemical libraries using normal and glioma-derived neural stem cell lines.Methods Enzymol. 506:311-29.
Falk A, Koch P, Kesavan J, Takashima Y, Ladewig J, Alexander M, Wiskow O, Tailor J, Trotter M, Pollard SM et al..  2012.  Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons.PLoS One. 7(1):e29597.
Engström PG, Tommei D, Stricker SH, Ender C, Pollard SM, Bertone P.  2012.  Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival.Genome Med. 4(10):76.

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