Leading science, pioneering therapies

Neural stem cells and brain cancer group publications

2017

Ingallina C, Costa PM, Ghirga F, Klippstein R, Wang JT, Berardozzi S, Hodgins N, Infante P, Pollard SM, Botta B et al..  2017.  Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro.Nanomedicine (Lond). 12(7):711-728.
Garcia I, Aldaregia J, Vicentic JMarjanovic, Aldaz P, Moreno-Cugnon L, Torres-Bayona S, Carrasco-Garcia E, Garros-Regulez L, Egaña L, Rubio A et al..  2017.  Oncogenic activity of SOX1 in glioblastoma.Sci Rep. 7:46575.
Martella A, Matjusaitis M, Auxillos J, Pollard SM, Cai Y.  2017.  EMMA: An Extensible Mammalian Modular Assembly Toolkit for the Rapid Design and Production of Diverse Expression Vectors.ACS Synth Biol.
Bulstrode H, Johnstone E, Marqués-Torrejón MÁngeles, Ferguson KM, Bressan RBardini, Blin C, Grant V, Gogolok S, Gangoso E, Gagrica S et al..  2017.  Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators.Genes Dev. 31(8):757-773.
Bressan RBardini, Dewari PSingh, Kalantzaki M, Gangoso E, Matjusaitis M, Garcia-Diaz C, Blin C, Grant V, Bulstrode H, Gogolok S et al..  2017.  Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.Development. 144(4):635-648.

2016

Blake SM, Stricker SH, Halavach H, Poetsch AR, Cresswell G, Kelly G, Kanu N, Marino S, Luscombe NM, Pollard SM et al..  2016.  Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation.Elife. 5
Krusche B, Ottone C, Clements MP, Johnstone ER, Goetsch K, Lieven H, Mota SG, Singh P, Khadayate S, Ashraf A et al..  2016.  EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.Elife. 5
Gogolok S, Garcia-Diaz C, Pollard SM.  2016.  STAR: a simple TAL effector assembly reaction using isothermal assembly.Sci Rep. 6:33209.
Pollard SM.  2016.  Quantitative stem cell biology: the threat and the glory.Development. 143(22):4097-4100.
Okawa S, Gagrica S, Blin C, Ender C, Pollard SM, Krijgsveld J.  2016.  Proteome and Secretome Characterization of Glioblastoma-Derived Neural Stem Cells.Stem Cells.
Carén H, Beck S, Pollard SM.  2016.  Differentiation therapy for glioblastoma – too many obstacles?Molecular & Cellular Oncology. 3(2):e1124174.
Martella A, Pollard SM, Dai J, Cai Y.  2016.  Mammalian Synthetic Biology: Time for Big MACs.ACS Synth Biol.
Garros-Regulez L, Aldaz P, Arrizabalaga O, Moncho-Amor V, Carrasco-Garcia E, Manterola L, Moreno-Cugnon L, Barrena C, Villanua J, Ruiz I et al..  2016.  mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.Expert Opin Ther Targets. 20(4):393-405.
Pollard SM, M Marqués-Torrejón Á.  2016.  Give it a REST!Elife. 5

2015

Carén H, Stricker SH, Bulstrode H, Gagrica S, Johnstone E, Bartlett TE, Feber A, Wilson G, Teschendorff AE, Bertone P et al..  2015.  Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest.Stem Cell Reports.
Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H et al..  2015.  Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.Cell Rep.

2014

2013

Pollard SM.  2013.  In vitro expansion of fetal neural progenitors as adherent cell lines.Methods Mol Biol. 1059:13-24.
Sofueva S, Yaffe E, Chan W-C, Georgopoulou D, Rudan MVietri, Mira-Bontenbal H, Pollard SM, Schroth GP, Tanay A, Hadjur S.  2013.  Cohesin-mediated interactions organize chromosomal domain architecture.EMBO J. 32(24):3119-29.

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