Leading science, pioneering therapies

Myelination and repair in the CNS group publications

2017

Raven A, Lu W-Y, Man TYung, Ferreira-González S, O'Duibhir E, Dwyer BJ, Thomson JP, Meehan RR, Bogorad R, Koteliansky V et al..  2017.  Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.Nature.

2016

Gee HYung, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J et al..  2016.  FAT1 mutations cause a glomerulotubular nephropathy.Nat Commun. 7:10822.
Ahmed M, ffrench-Constant C.  2016.  Extracellular Matrix Regulation of Stem Cell Behavior.Curr Stem Cell Rep. 2:197-206.
Licht T, Rothe G, Kreisel T, Wolf B, Benny O, Rooney AG, ffrench-Constant C, Enikolopov G, Keshet E.  2016.  VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis.Proc Natl Acad Sci U S A. 113(48):E7828-E7836.
Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C.  2016.  Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin.Nat Commun. 7:10354.

2015

Seiberlich V, Bauer NG, Schwarz L, ffrench-Constant C, Goldbaum O, Richter-Landsberg C.  2015.  Downregulation of the microtubule associated protein Tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytesGlia. 63(9):1621-1635.
de la Fuente AGuzman, Errea O, van Wijngaarden P, Gonzalez GA, Kerninon C, Jarjour AA, Lewis HJ, Jones CA, Nait-Oumesmar B, Zhao C et al..  2015.  Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation.J Cell Biol. 211(5):975-85.
Bechler ME, Byrne L, ffrench-Constant C.  2015.  CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes.Curr Biol.
Megaw R, Mellough C, Wright A, Lako M, ffrench-Constant C.  2015.  Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa.Lancet. 385 Suppl 1:S69.
Jarjour AA, Boyd A, Dow LE, Holloway RK, Goebbels S, Humbert PO, Williams AC, ffrench-Constant C.  2015.  The polarity protein scribble regulates myelination and remyelination in the central nervous system.PLoS Biol. 13(3):e1002107.
Harrisingh MC, ffrench-Constant C.  2015.  Can the irradiated brain be salvaged by oligodendrocyte precursor transplantation?Cell Stem Cell. 16(2):113-4.

2014

Theocharidis U, Long K, ffrench-Constant C, Faissner A.  2014.  Regulation of the neural stem cell compartment by extracellular matrix constituents.Prog Brain Res. 214:3-28.
Chandran JS, Kazanis I, Clapcote SJ, Ogawa F, J Millar K, Porteous DJ, ffrench-Constant C.  2014.  Disc1 variation leads to specific alterations in adult neurogenesis.PLoS One. 9(10):e108088.
Pouwels PJW, Vanderver A, Bernard G, Wolf NI, Dreha-Kulczewksi SF, Deoni SCL, Bertini E, Kolschütter A, Richardson W, ffrench-Constant C et al..  2014.  Hypomyelinating leukodystrophies: Translational research progress and prospects.Ann Neurol.
Bechler ME, ffrench-Constant C.  2014.  Neuroscience. A new wrap for neuronal activity?Science. 344(6183):480-1.

2013

Czopka T, ffrench-Constant C, Lyons DA.  2013.  Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo.Dev Cell. 25(6):599-609.
Barateiro A, Miron VE, Santos SD, Relvas JB, Fernandes A, ffrench-Constant C, Brites D.  2013.  Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination.Mol Neurobiol. 47(2):632-44.
Stoffels JMJ, de Jonge JC, Stancic M, Nomden A, van Strien ME, Ma D, Sisková Z, Maier O, ffrench-Constant C, Franklin RJM et al..  2013.  Fibronectin aggregation in multiple sclerosis lesions impairs remyelination.Brain. 136(Pt 1):116-31.
Yuen TJ, Johnson KR, Miron VE, Zhao C, Quandt J, Harrisingh MC, Swire M, Williams AC, McFarland HF, Franklin RJM et al..  2013.  Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination.Brain. 136(Pt 4):1035-47.
Miron VE, Boyd A, Zhao J-W, Yuen TJ, Ruckh JM, Shadrach JL, van Wijngaarden P, Wagers AJ, Williams AC, Franklin RJM et al..  2013.  M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination.Nat Neurosci. 16(9):1211-8.

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