Leading science, pioneering therapies

Mechanisms of regeneration with age group publications

2018

Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM.  2018.  Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.EMBO Mol Med.

2017

Farmer D'J, Nathan S, Finley J, Yu KShengyang, Emmerson E, Byrnes L, Sneddon J, McManus M, Tward A, Knox S.  2017.  Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.Development.
Togarrati PPriya, Sasaki RT, Abdel-Mohsen M, Dinglasan N, Deng X, Desai S, Emmerson E, Yee E, Ryan WR, da Silva MCP et al..  2017.  Identification and characterization of a rich population of CD34(+) mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands.Sci Rep. 7(1):3484.
Emmerson E, May A, Nathan S, Pacheco NCruz, Lizama CO, Maliskova L, Zovein AC, Shen Y, Muench MO, Knox SM.  2017.  SOX2 regulates acinar cell development in the salivary gland.Elife. 6

2014

Finley JK, Farmer D'J, Emmerson E, Pacheco NCruz, Knox SM.  2014.  Manipulating the murine lacrimal gland.J Vis Exp. (93):e51970.
Nedvetsky PI, Emmerson E, Finley JK, Ettinger A, Cruz-Pacheco N, Prochazka J, Haddox CL, Northrup E, Hodges C, Mostov KE et al..  2014.  Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.Dev Cell. 30(4):449-62.
Campbell L, Emmerson E, Williams H, Saville CR, Krust A, Chambon P, Mace KA, Hardman MJ.  2014.  Estrogen receptor-alpha promotes alternative macrophage activation during cutaneous repair.J Invest Dermatol. 134(9):2447-57.

2013

Emmerson E, Rando G, Meda C, Campbell L, Maggi A, Hardman MJ.  2013.  Estrogen receptor-mediated signalling in female mice is locally activated in response to wounding.Mol Cell Endocrinol. 375(1-2):149-56.

2012

Emmerson E, Hardman MJ.  2012.  The role of estrogen deficiency in skin ageing and wound healing.Biogerontology. 13(1):3-20.
Emmerson E, Campbell L, Davies FCJ, Ross NL, Ashcroft GS, Krust A, Chambon P, Hardman MJ.  2012.  Insulin-like growth factor-1 promotes wound healing in estrogen-deprived mice: new insights into cutaneous IGF-1R/ERα cross talk.J Invest Dermatol. 132(12):2838-48.

2011

Gilliver SC, Emmerson E, Bernhagen J, Hardman MJ.  2011.  MIF: a key player in cutaneous biology and wound healing.Exp Dermatol. 20(1):1-6.

2010

Emmerson E, Campbell L, Ashcroft GS, Hardman MJ.  2010.  The phytoestrogen genistein promotes wound healing by multiple independent mechanisms.Mol Cell Endocrinol. 321(2):184-93.
Gilliver SC, Emmerson E, Campbell L, Chambon P, Hardman MJ, Ashcroft GS.  2010.  17beta-estradiol inhibits wound healing in male mice via estrogen receptor-alpha.Am J Pathol. 176(6):2707-21.
Campbell L, Emmerson E, Davies F, Gilliver SC, Krust A, Chambon P, Ashcroft GS, Hardman MJ.  2010.  Estrogen promotes cutaneous wound healing via estrogen receptor beta independent of its antiinflammatory activities.J Exp Med. 207(9):1825-33.

2009

2008

Hardman MJ, Emmerson E, Campbell L, Ashcroft GS.  2008.  Selective estrogen receptor modulators accelerate cutaneous wound healing in ovariectomized female mice.Endocrinology. 149(2):551-7.