Leading science, pioneering therapies

Mechanisms of neurodegeneration group publications

2017

Drummond N, Davies NO, Lovett JE, Miller MR, Cook G, Becker T, Becker CG, McPhail DB, Kunath T.  2017.  A synthetic cell permeable antioxidant protects neurons against acute oxidative stressScientific Reports. (1Suppl)
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A et al..  2017.  The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.Sci Transl Med. 9(391)
Dolt KSingh, Hammachi F, Kunath T.  2017.  Modeling Parkinson's disease with induced pluripotent stem cells harboring α-synuclein mutations.Brain Pathol. 27(4):545-551.
Amorim IS, Graham LC, Carter RN, Morton NM, Hammachi F, Kunath T, Pennetta G, Carpanini SM, Manson JC, Lamont DJ et al..  2017.  Sideroflexin 3 is an α-synuclein-dependent mitochondrial protein that regulates synaptic morphology.J Cell Sci. 130(2):325-331.

2016

de Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Allan D et al..  2016.  Derivation of the clinical grade human embryonic stem cell line RCe021-A (RC-17).Stem Cell Res. 17(1):1-5.
de Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Canham MA et al..  2016.  Derivation of the clinical grade human embryonic stem cell line RCe013-A (RC-9).Stem Cell Res. 17(1):36-41.
de Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A et al..  2016.  Derivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11).Stem Cell Res. 17(1):42-48.
Sotthibundhu A, McDonagh K, von Kriegsheim A, Garcia-Munoz A, Klawiter A, Thompson K, Chauhan KDev, Krawczyk J, McInerney V, Dockery P et al..  2016.  Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells.Stem Cell Res Ther. 7(1):166.

2015

Canham MA, Van Deusen A, Brison DR, De Sousa PA, Downie J, Devito L, Hewitt ZA, Ilic D, Kimber SJ, Moore HD et al..  2015.  The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell Lines.Sci Rep. 5:17258.
Holmqvist S, Brouwer M, Djelloul M, Diaz AGarcia, Devine MJ, Hammarberg A, Fog K, Kunath T, Roybon L.  2015.  Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors.Stem Cell Res. 15(1):203-20.
Sposito T, Preza E, Mahoney CJ, Salvia úriaó-, Ryan NS, Morris HR, Arber C, Devine MJ, Houlden H, Warner TT et al..  2015.  Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPTHuman Molecular Genetics. 24(18):5260-5269.
Phillips AS, Gomes AF, Kalapothakis JMD, Gillam JE, Gasparavicius J, Gozzo FC, Kunath T, MacPhee C, Barran PE.  2015.  Conformational dynamics of α-synuclein: insights from mass spectrometryThe Analyst. 140(9):3070-3081.
Holmqvist S, Brouwer M, Djelloul M, Diaz AGarcia, Devine MJ, Hammarberg A, Fog K, Kunath T, Roybon L.  2015.  Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitorsStem Cell Research. 15(1):203-220.
Canham MA, Van Deusen A, Brison DR, De Sousa PA, Downie J, Devito L, Hewitt ZA, Ilic D, Kimber SJ, Moore HD et al..  2015.  The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell LinesScientific Reports. 5:17258.

2014

Kunath T, Yamanaka Y, Detmar J, MacPhee D, Caniggia I, Rossant J, Jurisicova A.  2014.  Developmental differences in the expression of FGF receptors between human and mouse embryos.Placenta. 35(12):1079-88.
Kunath T, Yamanaka Y., Detmar J., MacPhee D., Caniggia I., Rossant J., Jurisicova A..  2014.  Developmental differences in the expression of FGF receptors between human and mouse embryosPlacenta.

2013

2012

Paca A, Séguin CA, Clements M, Ryczko M, Rossant J, Rodriguez TA, Kunath T.  2012.  BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm.Dev Biol. 361(1):90-102.

2011

Drummond RJ, Kunath T, Mee PJ, Ross JA.  2011.  Induced pluripotent stem cell technology and stem cell therapy for diabetes.Exp Ther Med. 2(1):3-7.

Pages