Facilities

CRM has the following in-house facilities:

  • Centralised cell culture facility for isolation and culture of both mouse and human embryonic stem cells
  • Transgenic facility covering provision of mouse ES cells, blastocyst injection, derivation of custom mouse ES cell lines and other embryo manipulations
  • Operator-run flow cytometry service (Cytomation MoFlo and Becton-Dickinson FacsCalibur – 6 parameter, 4 colour sorting; Dako-Cytomation – 8 parameter 6 colour sorting)
  • Quantitative real-time PCR
  • Automated in situ hybridisation
  • Histology
  • Facilities for the manufacture of solid free-form bioactive devices, for in vivo delivery of cells
  • SPF animal facilities
  • Imaging facility

CRM researchers have ready access to the following facilities:

  • Sequencing and proteomics facilities
  • Fermenters for large scale protein production
  • Zebrafish facility
  • Clinical research imaging centre
  • BHF Biomedical Magnetic Resonance Imaging Unit
  • Wellcome Trust Clinical Trials Unit