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Found 103 results
Filters: Keyword is Mice, Knockout  [Clear All Filters]
2002
Rambukkana A, Zanazzi G, Tapinos N, Salzer JL.  2002.  Contact-dependent demyelination by Mycobacterium leprae in the absence of immune cells.Science. 296(5569):927-31.
Kawagoe J, Takizawa T, Matsumoto J, Tamiya M, Meek SE, Smith AG, Hunter GD, Plevin R, Saito N, Kanke T et al..  2002.  Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear.Jpn J Pharmacol. 88(1):77-84.
Houzelstein D, Bullock SL, Lynch DE, Grigorieva EF, Wilson V, Beddington RS.  2002.  Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.Mol Cell Biol. 22(11):3794-802.
2001
Bamforth SD, Bragança J, Eloranta JJ, Murdoch JN, Marques FI, Kranc KR, Farza H, Henderson DJ, Hurst HC, Bhattacharya S.  2001.  Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.Nat Genet. 29(4):469-74.
Davies B, Kearns IR, Ure J, Davies CH, Lathe R.  2001.  Loss of hippocampal serine protease BSP1/neuropsin predisposes to global seizure activity.J Neurosci. 21(18):6993-7000.
Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schöfer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A et al..  2001.  Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.Cell. 107(3):323-37.
Ottersbach K, Cook DN, Kuziel WA, Humbles A, Lu B, Gerard C, Proudfoot AE, Graham GJ.  2001.  Macrophage inflammatory protein-1alpha uses a novel receptor for primitive hemopoietic cell inhibition.Blood. 98(12):3476-8.
Rose K, Allan A, Gauldie S, Stapleton G, Dobbie L, Dott K, Martin C, Wang L, Hedlund E, Seckl JR et al..  2001.  Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation.J Biol Chem. 276(26):23937-44.
Nichols J, Chambers I, Taga T, Smith A.  2001.  Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines.Development. 128(12):2333-9.
2000
Nicklin MJ, Hughes DE, Barton JL, Ure JM, Duff GW.  2000.  Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene.J Exp Med. 191(2):303-12.
Gillespie CS, Sherman DL, Fleetwood-Walker SM, Cottrell DF, Tait S, Garry EM, Wallace VC, Ure J, Griffiths IR, Smith A et al..  2000.  Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice.Neuron. 26(2):523-31.
Bucher K, Sofroniew MV, Pannell R, Impey H, Smith AG, Torres EM, Dunnett SB, Jin Y, Baer R, Rabbitts TH.  2000.  The T cell oncogene Tal2 is necessary for normal development of the mouse brain.Dev Biol. 227(2):533-44.
1999
Wei XQ, Leung BP, Niedbala W, Piedrafita D, Feng GJ, Sweet M, Dobbie L, Smith AG, Liew FY.  1999.  Altered immune responses and susceptibility to Leishmania major and Staphylococcus aureus infection in IL-18-deficient mice.J Immunol. 163(5):2821-8.
Pagès G, Guérin S, Grall D, Bonino F, Smith A, Anjuere F, Auberger P, Pouysségur J.  1999.  Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice.Science. 286(5443):1374-7.
Kotelevtsev Y, Brown WR, Fleming S, Kenyon CJ, Edwards CR, Seckl JR, Mullins JJ.  1999.  Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.J Clin Invest. 103(5):683-9.
Aubert J, Dessolin S, Belmonte N, Li M, McKenzie FR, Staccini L, Villageois P, Barhanin B, Vernallis A, Smith AG et al..  1999.  Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade.J Biol Chem. 274(35):24965-72.
Pérarnau B, Saron MF, B San Martin R, Bervas N, Ong H, Soloski MJ, Smith AG, Ure JM, Gairin JE, Lemonnier FA.  1999.  Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses.Eur J Immunol. 29(4):1243-52.
Akopian AN, Souslova V, England S, Okuse K, Ogata N, Ure J, Smith A, Kerr BJ, McMahon SB, Boyce S et al..  1999.  The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways.Nat Neurosci. 2(6):541-8.
1998
Butcher JW, De Felipe C, Smith AG, Hunt SP, Paton JF.  1998.  Comparison of cardiorespiratory reflexes in NK1 receptor knockout, heterozygous and wild-type mice in vivo.J Auton Nerv Syst. 69(2-3):89-95.
Wastling JM, Knight P, Ure J, Wright S, Thornton EM, Scudamore CL, Mason J, Smith A, Miller HR.  1998.  Histochemical and ultrastructural modification of mucosal mast cell granules in parasitized mice lacking the beta-chymase, mouse mast cell protease-1.Am J Pathol. 153(2):491-504.
Sprengel R, Suchanek B, Amico C, Brusa R, Burnashev N, Rozov A, Hvalby O, Jensen V, Paulsen O, Andersen P et al..  1998.  Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.Cell. 92(2):279-89.
Henderson CJ, Smith AG, Ure J, Brown K, Bacon EJ, Wolf CR.  1998.  Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases.Proc Natl Acad Sci U S A. 95(9):5275-80.
1997
Kotelevtsev Y, Holmes MC, Burchell A, Houston PM, Schmoll D, Jamieson P, Best R, Brown R, Edwards CR, Seckl JR et al..  1997.  11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress.Proc Natl Acad Sci U S A. 94(26):14924-9.
Pascolo S, Bervas N, Ure JM, Smith AG, Lemonnier FA, Pérarnau B.  1997.  HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice.J Exp Med. 185(12):2043-51.
Schrank B, Götz R, Gunnersen JM, Ure JM, Toyka KV, Smith AG, Sendtner M.  1997.  Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos.Proc Natl Acad Sci U S A. 94(18):9920-5.

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