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CRM Publications

Found 24 results
Filters: Keyword is DNA Methylation  [Clear All Filters]
2017
Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M et al..  2017.  DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.Proc Natl Acad Sci U S A. 114(36):E7526-E7535.
2016
Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth R, Webb S, Kerr ARW, Lyall MJ et al..  2016.  Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.Cancer Res. 76(10):3097-108.
2015
Illingworth R, Gruenewald-Schneider U, De Sousa D, Webb S, Merusi C, Kerr ARW, James KD, Smith C, Walker R, Andrews R et al..  2015.  Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome.Nucleic Acids Res. 43(2):732-44.
2014
Schultze FChristian, Andag R, Alwahsh SMohammad, Toncheva D, Maslyankov S, Yaramov N, von Ahsen N, Brandhorst G, Walson PD, Oellerich M et al..  2014.  FoxP3 demethylation is increased in human colorectal cancer and rat cholangiocarcinoma tissue.Clin Biochem. 47(3):201-5.
2013
Carén H, Pollard SM, Beck S.  2013.  The good, the bad and the ugly: epigenetic mechanisms in glioblastoma.Mol Aspects Med. 34(4):849-62.
Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M, Vasiliauskaite L, Benes V, Enright AJ, O'Carroll D.  2013.  Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.Mol Cell. 50(4):601-8.
Stricker SH, Feber A, Engström PG, Carén H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P et al..  2013.  Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner.Genes Dev. 27(6):654-69.
2012
Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, Lee J-H, Skalnik D, Bird A.  2012.  Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.Genes Dev. 26(15):1714-28.
Lynch MD, Smith AG, De Gobbi M, Flenley M, Hughes J, Vernimmen D, Ayyub H, Sharpe JA, Sloane-Stanley JA, Sutherland L et al..  2012.  An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.EMBO J. 31(2):317-29.
2011
Deaton AM, Webb S, Kerr ARW, Illingworth R, Guy J, Andrews R, Bird A.  2011.  Cell type-specific DNA methylation at intragenic CpG islands in the immune system.Genome Res. 21(7):1074-86.
Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G et al..  2011.  Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 21(9):1332-42.
2010
Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr ARW, Deaton A, Andrews R, James KD et al..  2010.  CpG islands influence chromatin structure via the CpG-binding protein Cfp1.Nature. 464(7291):1082-6.
Skene PJ, Illingworth R, Webb S, Kerr ARW, James KD, Turner DJ, Andrews R, Bird AP.  2010.  Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.Mol Cell. 37(4):457-68.
Illingworth R, Gruenewald-Schneider U, Webb S, Kerr ARW, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.  2010.  Orphan CpG islands identify numerous conserved promoters in the mammalian genome.PLoS Genet. 6(9):e1001134.
Barakat TStefan, Jonkers I, Monkhorst K, Gribnau J.  2010.  X-changing information on X inactivation.Exp Cell Res. 316(5):679-87.
2009
Illingworth R, Bird AP.  2009.  CpG islands--'a rough guide'.FEBS Lett. 583(11):1713-20.
2008
Hayashi K, Lopes SMChuva de, Kaneda M, Tang F, Hajkova P, Lao K, O'Carroll D, Das PP, Tarakhovsky A, Miska EA et al..  2008.  MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.PLoS One. 3(3):e1738.
Illingworth R, Kerr A, Desousa D, Jørgensen H, Ellis P, Stalker J, Jackson D, Clee C, Plumb R, Rogers J et al..  2008.  A novel CpG island set identifies tissue-specific methylation at developmental gene loci.PLoS Biol. 6(1):e22.
2006
Garrick D, Sharpe JA, Arkell R, Dobbie L, Smith AG, Wood WG, Higgs DR, Gibbons RJ.  2006.  Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues.PLoS Genet. 2(4):e58.
Blelloch R, Wang Z, Meissner A, Pollard SM, Smith A, Jaenisch R.  2006.  Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus.Stem Cells. 24(9):2007-13.
2004
Jackson M, Krassowska A, Gilbert N, Chevassut T, Forrester LM, Ansell JD, Ramsahoye B.  2004.  Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.Mol Cell Biol. 24(20):8862-71.
2003
Hendrich B, Tweedie S.  2003.  The methyl-CpG binding domain and the evolving role of DNA methylation in animals.Trends Genet. 19(5):269-77.
2002
Prokhortchouk E, Hendrich B.  2002.  Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs?Oncogene. 21(35):5394-9.
2001
Hendrich B, Guy J, Ramsahoye B, Wilson V, Bird A.  2001.  Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.Genes Dev. 15(6):710-23.