CRM Publications

Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M et al..  2017.  DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.Proc Natl Acad Sci U S A. 114(36):E7526-E7535.

Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth R, Webb S, Kerr ARW, Lyall MJ et al..  2016.  Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.Cancer Res. 76(10):3097-108.

Schultze FChristian, Andag R, Alwahsh SMohammad, Toncheva D, Maslyankov S, Yaramov N, von Ahsen N, Brandhorst G, Walson PD, Oellerich M et al..  2014.  FoxP3 demethylation is increased in human colorectal cancer and rat cholangiocarcinoma tissue.Clin Biochem. 47(3):201-5.

Torres-Padilla M-E, Chambers I.  2014.  Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage.Development. 141(11):2173-81.

de Wit E, Bouwman BAM, Zhu Y, Klous P, Splinter E, Verstegen MJAM, Krijger PHL, Festuccia N, Nora EP, Welling M et al..  2013.  The pluripotent genome in three dimensions is shaped around pluripotency factors.Nature. 501(7466):227-31.

Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, Lee J-H, Skalnik D, Bird A.  2012.  Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.Genes Dev. 26(15):1714-28.

Devoy A, Bunton-Stasyshyn RKA, Tybulewicz VLJ, Smith AG, Fisher EMC.  2012.  Genomically humanized mice: technologies and promises.Nat Rev Genet. 13(1):14-20.

Balikova A, Jääger K, Viil J, Maimets T, Kadaja-Saarepuu L.  2012.  Leukocyte marker CD43 promotes cell growth in co-operation with β-catenin in non-hematopoietic cancer cells.Int J Oncol. 41(1):299-309.

Illingworth R, Botting CH, Grimes GR, Bickmore WA, Eskeland R.  2012.  PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.PLoS One. 7(4):e34848.

Deaton AM, Webb S, Kerr ARW, Illingworth R, Guy J, Andrews R, Bird A.  2011.  Cell type-specific DNA methylation at intragenic CpG islands in the immune system.Genome Res. 21(7):1074-86.

Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr ARW, Deaton A, Andrews R, James KD et al..  2010.  CpG islands influence chromatin structure via the CpG-binding protein Cfp1.Nature. 464(7291):1082-6.

Navarro P, Oldfield A, Legoupi J, Festuccia N, Dubois A, Attia M, Schoorlemmer J, Rougeulle C, Chambers I, Avner P.  2010.  Molecular coupling of Tsix regulation and pluripotency.Nature. 468(7322):457-60.

Illingworth R, Gruenewald-Schneider U, Webb S, Kerr ARW, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.  2010.  Orphan CpG islands identify numerous conserved promoters in the mammalian genome.PLoS Genet. 6(9):e1001134.

Bee T, Liddiard K, Swiers G, Bickley SRB, Vink CS, Jarratt A, Hughes J, Medvinsky AL, de Bruijn MFTR.  2009.  Alternative Runx1 promoter usage in mouse developmental hematopoiesis.Blood Cells Mol Dis. 43(1):35-42.

Kallis YN, Forbes SJ.  2009.  The bone marrow and liver fibrosis: friend or foe?Gastroenterology. 137(4):1218-21.

Vernimmen D, Marques-Kranc F, Sharpe JA, Sloane-Stanley JA, Wood WG, Wallace HAC, Smith AG, Higgs DR.  2009.  Chromosome looping at the human alpha-globin locus is mediated via the major upstream regulatory element (HS -40).Blood. 114(19):4253-60.

Illingworth R, Bird AP.  2009.  CpG islands--'a rough guide'.FEBS Lett. 583(11):1713-20.

Tsakiridis A, Tzouanacou E, Rahman A, Colby D, Axton RA, Chambers I, Wilson V, Forrester LM, Brickman JM.  2009.  Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells.Nucleic Acids Res. 37(19):e129.

Leimgruber E, Seguín-Estévez Q, Dunand-Sauthier I, Rybtsova N, Schmid CD, Ambrosini G, Bucher P, Reith W.  2009.  Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site.Nucleic Acids Res. 37(8):2514-28.

Jacobs FMJ, van Erp S, van der Linden AJA, von Oerthel L, J Burbach PH, Smidt MP.  2009.  Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression.Development. 136(4):531-40.

Morrison GM, Oikonomopoulou I, Migueles RPortero, Soneji S, Livigni A, Enver T, Brickman JM.  2008.  Anterior definitive endoderm from ESCs reveals a role for FGF signaling.Cell Stem Cell. 3(4):402-15.

Bilican B, Fiore-Heriche C, Compston A, Allen ND, Chandran S.  2008.  Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad level.PLoS One. 3(8):e2863.

Bru T, Clarke C, McGrew MJ, Sang HM, Wilmut I, J Blow J.  2008.  Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts.Exp Cell Res. 314(14):2634-42.

Blelloch R, Wang Z, Meissner A, Pollard SM, Smith A, Jaenisch R.  2006.  Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus.Stem Cells. 24(9):2007-13.

Doumont G, Martoriati A, Beekman C, Bogaerts S, Mee PJ, Bureau F, Colombo E, Alcalay M, Bellefroid E, Marchesi F et al..  2005.  G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv.EMBO J. 24(17):3093-103.