Leading science, pioneering therapies

The MRC Centre for Regenerative Medicine (CRM) is a research institute based at the University of Edinburgh. Scientists and clinicians study stem cells, disease and tissue repair to advance human health.

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New and noted
Notch3 expression in liver cancer

New clues to cause of bile duct cancer

Scientists at the CRM have identified a molecule that drives the development of bile duct cancer.  The research in mice and human cells sheds new light on what triggers the disease and how the illness progresses.

Cell Reports study

Dr Katrin Ottersbach: "Our findings reveal the first changes that take place in blood development caused by the MLL-AF4 mutation during a pre-cancerous state."

MRC funding to improve iPS technology

Dr Abdenour Soufi awarded £1.8M for novel synthetic factors to improve iPS technology.

Stem Cells Transl Med

New study shows a potential future treatment for paracetamol overdose and that stem cell derived liver cells can act as a good model of drug toxicity in the liver.