Leading science, pioneering therapies

The MRC Centre for Regenerative Medicine (CRM) is a research institute based at the University of Edinburgh. Scientists and clinicians study stem cells, disease and tissue repair to advance human health.

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Stem Cells Transl Med

New study shows a potential future treatment for paracetamol overdose and that stem cell derived liver cells can act as a good model of drug toxicity in the liver.

Nature Communications

Three key molecules, Sonic Hedgehog, Stem Cell factor and Noggin, interact together to generate blood stem cells in the embryo. Prof Medvinsky: "This brings us one step closer to making them in the lab for treatments".

Blood publication

Research by Dr. Katrin Ottersbach shows that embryonic blood stem cells are resistant to the JAK2V617F mutation, normally associated with the development of myeloproliferative blood disorders (MPD) in adults.

EMBO Journal

Dr Gillian Morrison: Our works shows how we can accurately instruct a cell what to become by controlling the signals it receives. By studying this we aim to develop efficient protocols to cells in a dish towards specialised cell types such as beta cells to treat Diabetes.